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(SADI Bypass Surgery) Single Anastomosis Duodenal-Ileal Bypass

It is a type of weight loss surgery that offers promising results for individuals struggling with obesity. It reduces the size of the stomach, leading to a decreased food intake as it can hold less food around 100-150 ml. Additionally, by creating a connection between the duodenum and the ileum, the surgery bypasses a significant portion of the small intestine, reducing the absorption of calories and nutrients from the food. This alteration also influences the release of hormones that control hunger, satiety, and metabolism, helping to control appetite and promote weight loss.

SADI Surgery Patient Review

The importance of Bypassing the Duodenum

The duodenum is the first part of the small intestine, located just below the stomach. When food leaves the stomach, it enters the duodenum, where several important digestive processes take place.

However, in obese individuals, the duodenum can experience various dysfunctions that contribute to obesity and related health problems. The duodenum plays a role in releasing hormones that regulate hunger and satiety. In obesity, hormonal imbalances can occur, leading to reduced sensitivity to satiety hormones and increased production of hunger-inducing hormones like ghrelin. This can result in overeating and difficulty feeling full, leading to excess calorie intake and weight gain. Insulin resistance can negatively affect the duodenum’s ability to regulate blood sugar levels and may contribute to metabolic disturbances and lead to higher insulin levels. Elevated insulin levels can promote fat storage and hinder fat breakdown, leading to weight gain.

The SADI bypass surgery offers several benefits by partially removing the duodenum. During the procedure, a portion of the duodenum is bypassed, reducing the absorption of calories and nutrients from food. Additionally, hormonal changes occur, helping control appetite and further promoting weight reduction. The surgery has shown positive effects on insulin sensitivity, which benefits blood sugar control, particularly for patients with type 2 diabetes. By preserving some functions of the duodenum while achieving weight loss, the SADI bypass presents a comprehensive approach to managing obesity and related health conditions.

Weight loss with SADI Bypass Surgery

You can lose up to 45% of your total body weight through this procedure. By making lifestyle changes, you can increase it by 5%, and using medicines can add another 10%. In total, you can achieve a 60% reduction in your total body weight with this procedure.

It is highly beneficial for individuals with strong hunger feelings and those who experience frequent and persistent hunger. This procedure is often used for very obese individuals because it offers one of the most aggressive weight loss results provided by bariatric surgery. For example, if a person with a BMI of 50 undergoes the SADI bypass, they can lose up to 20 BMI points and achieve a BMI of 30 or even lower, moving them out of the danger zone of obesity and towards a healthier weight range.


During the SADI bypass surgery, the surgeon makes minor cuts in the abdomen. The first step involves creating a sleeve gastrectomy, where a portion of the stomach is removed to make it smaller. Next, the initial segment of the first part of the small intestine (duodenum) is separated from the rest of the duodenum. Then the last 300-350 cm of the small intestine is measured, and the surgeon creates a connection between the duodenum and the last part of the small intestine (ileum). This connection helps bypass a significant part of the small intestine, leading to reduced absorption of calories and nutrients, which ultimately promotes weight loss. After completing the procedure, the incisions are closed. It’s essential for patients to follow post-operative care and make necessary lifestyle changes to support their weight loss journey effectively.

At ALSA Pakistan, Dr. Tahir Yunus performs this procedure with exceptional expertise and unrivaled skillfulness. He strives to help patients achieve significant weight loss and improve their overall health. You can feel confident in his experienced hands, and trust him with your well-being.

Follow-up and Lifestyle Changes

After the SADI Bypass Surgery, follow-up care and lifestyle changes are essential for successful outcomes and maintaining weight loss. Patients can expect regular post-operative check-ups with our healthcare team to monitor progress and address any concerns. You will receive guidance on adopting a balanced and nutrient-rich diet that suits your new digestive system, focusing on smaller, frequent meals and adequate protein intake. Physical activity is encouraged to support weight loss and overall health. You will need to take your prescribed vitamin and mineral supplements to prevent deficiencies due to reduced nutrient absorption. 

Benefits of SADI Bypass Surgery

This procedure offers several benefits for individuals struggling with obesity and related health conditions:

  • 1Lower chances of marginal ulcers as there is no direct connection of the small intestine with the stomach.
  • 2besity-related health conditions, such as sleep apnea, joint pain, and fatty liver disease, can improve or resolve after the surgery.
  • 3Best weight loss possible.
  • 4The control valve called Pylorus, present at the end of the stomach, is preserved in this procedure. It slows down the release of food into the small intestine. Hence, fluctuations in sugar level do not occur and the unpleasant dumping syndrome is also avoided. Resulting in a much more comfortable weight loss experience.

Following are a few drawbacks of
SADI Bypass Surgery;

  • Higher risk of vitamin deficiencies, approximately 30% .
  • 8% chance of protein malnutrition.
  • Increased frequency of gas passage throughout the day.
  • Increased number of times to go to the bathroom for passing stool.

However, very rarely these complications are too severe and regular follow-up and proper nutritional management can help minimize risks and ensure a successful outcome.